Q&A of the Week: Primary Peritoneal Carcinoma
Karen writes: My sister has been diagnosed with Primary Peritoneal Carcinoma. Her doctor says that this is the same thing as ovarian cancer, except not in the ovary! This makes no sense to me. Can you explain it? Also, does it run in families?
Karen-
Primary peritoneal carcinoma, which is cancer in the abdominal lining (the peritoneum), is very close to being exactly as your sister's doctor described. There is some debate whether or not it is exactly the same thing, but my take on it from my reading is "close enough". It looks the same as epithelial ovarian cancer (the most common type) under a microscope, it has the same symptoms, it spreads in a similar pattern, and it is treated the same way as ovarian cancer. And, like ovarian cancer, some cases probably have a genetic component. Specifically, the BRCA1 gene mutation, which is associated with both breast and ovarian cancers, may work similarly in primary peritoneal carcinoma (scientists aren't positive of this point). This by no means should make you think that all ovarian or peritoneal cancers are genetic, though - in both cases, most are not. Still, I advise you to consider yourself at some increased risk, and familiarize yourself with the risk factors, preventation and symptoms of ovarian cancer. The Prevention/Risks section of this site is a good place to start, as is this article about the early symptoms of ovarian cancer.
Primary peritoneal carcinoma, like ovarian cancer, is best treated by a gynecologic oncologist.
Best wishes to you and your sister -
Laura
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